Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html

Study Counts

Type Study_count
Total_Studies 113
interventional 94
Observational 17
Registry 2

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Drug|Other 14
Drug 13
Drug|Procedure 9
Procedure 9
Radiation 6
Biological|Drug|Other 5
Device 4
Drug|Other|placebo 3
Drug|Procedure|Radiation 3
Drug|Radiation 3
Behavioral 2
Biological|Drug|Other|Radiation 2
Drug|Other|Procedure|Radiation 2
Other 2
Procedure|Radiation 2
Behavioral|Other 1
Behavioral|Radiation 1
Biological 1
Biological|Device 1
Biological|Drug 1
Biological|Drug|Other|placebo|Procedure 1
Biological|Drug|Other|Procedure|Radiation 1
Biological|Drug|Radiation 1
Biological|Other|Radiation 1
Biological|Procedure|Radiation 1
Device|Procedure 1
Dietary Supplement|Procedure 1
Drug|Other|Radiation 1
Drug|placebo|Procedure 1
Other|Procedure 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 61
France 7
China 6
United Kingdom 3
Netherlands 2
Switzerland 2
United States|Canada 2
Austria 1
Belgium|Germany|Netherlands|Spain 1
Canada 1
Czech Republic 1
Denmark 1
India 1
Iran, Islamic Republic of 1
Saudi Arabia 1
Spain 1
United States|Canada|China 1
United States|Croatia|France|Russian Federation|Spain 1

Sites per Study

Site_count Study_Count
1 70
2 3
3 5
4 2
5 2
6 1
8 3
9 1
10 1
17 1
26 1
35 1
228 1
232 1
508 1

Phase

Phase Study_Count
Phase 2 34
N/A 20
Phase 1 20
Phase 1/Phase 2 12
Phase 3 5
Phase 2/Phase 3 3

Number of Arms

Number_of_Arms Count_of_Studies
1 45
2 31
3 5
4 2
5 2
NA 9

Enrollment Metrics by Phase

Measure N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3
Min. 9.00 3.0 15.00000 9.00000 120.0000 90.0
1st Qu. 29.50 12.0 29.25000 29.00000 321.5000 220.0
Median 48.00 24.0 62.00000 55.00000 523.0000 285.0
Mean 108.55 28.3 83.16667 68.15152 439.3333 685.6
3rd Qu. 162.50 41.5 80.50000 88.00000 599.0000 840.0
Max. 360.00 75.0 400.00000 204.00000 675.0000 1993.0

Trial Group Type

group_type Group_Count
Experimental 113
Active Comparator 16
NA 9
Placebo Comparator 6
Other 3
No Intervention 2

Intervention Model

intervention_model Study_Count
Single Group Assignment 49
Parallel Assignment 42
Factorial Assignment 1
Sequential Assignment 1
NA 1

Primary Purpose

primary_purpose Study_Count
Treatment 72
Supportive Care 11
Diagnostic 5
Prevention 4
Health Services Research 1
NA 1

Observational Studies

Studies by Country

Country Study_Count
United States 9
France 3
China 2
Australia 1
NA 1
Netherlands 1

Sites per Study

Site_count Study_Count
1 14
3 1
5 1
14 1

Enrollment Metrics

Measure Observational
Min 5.0000
1st Qu 54.0000
Median 93.0000
Mean 157.7059
3rd Qu 279.0000
Max 471.0000

Observation Model

observational_model Study_Count
Cohort 10
Case-Only 4
Case-Control 1
Other 1
NA 1

Time Perspective

time_perspective Study_Count
Prospective 13
Retrospective 3
NA 1

Registries

Studies by Country

Country Study_Count
United States 2

Sites per Study

Site_count Study_Count
1 1
75 1

Enrollment Metrics

Measure Registries
Min 1500.0
1st Qu 251124.8
Median 500749.5
Mean 500749.5
3rd Qu 750374.2
Max 999999.0

Registry Model

observational_model Study_Count
Cohort 2

Time Perspective

time_perspective Study_Count
Prospective 2

Follow-up

target_duration Study_Count
36 Months 1
80 Years 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT03292341 Evaluation of a Web-based Decision Aid Tool for Larynx Cancer (T3/T4) Patients. https://ClinicalTrials.gov/show/NCT03292341 Recruiting Maastricht Radiation Oncology 2020-05-31
NCT03114462 Trial of Stereotactic HYpofractionateD RadioAblative (HYDRA) Treatment of Laryngeal Cancer https://ClinicalTrials.gov/show/NCT03114462 Recruiting M.D. Anderson Cancer Center 2027-08-31
NCT03096808 Adaptive Radiotherapy for Head and Neck Cancer https://ClinicalTrials.gov/show/NCT03096808 Active, not recruiting Memorial Sloan Kettering Cancer Center 2021-03-15
NCT03082534 Pembrolizumab Combined With Cetuximab for Treatment of Recurrent/Metastatic Head & Neck Squamous Cell Carcinoma https://ClinicalTrials.gov/show/NCT03082534 Recruiting University of California, San Diego 2019-12-30
NCT03010813 A Novel Robotic System for Single Port and Natural Orifice Transluminal Endoscopic Surgery https://ClinicalTrials.gov/show/NCT03010813 Completed Chinese University of Hong Kong 2017-10-31
NCT02849314 Combination of Cryosurgey and NK Immunotherapy for Recurrent Laryngeal Cancer https://ClinicalTrials.gov/show/NCT02849314 Completed Fuda Cancer Hospital, Guangzhou 2017-07-01
NCT02757222 Dose Escalation Versus Standard in Laryngopharyngeal Cancers https://ClinicalTrials.gov/show/NCT02757222 Recruiting Tata Medical Center 2020-12-31
NCT02734537 Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery https://ClinicalTrials.gov/show/NCT02734537 Recruiting Eastern Cooperative Oncology Group 2022-05-01
NCT02586207 Pembrolizumab in Combination With CRT for LA-SCCHN https://ClinicalTrials.gov/show/NCT02586207 Active, not recruiting Sanford Health 2020-06-30
NCT03392220 A Multicenter, Randomized, Case-control Study of Unilateral vs Bilateral Neck Dissection for cN0 Supraglottic Laryngeal Cancer https://ClinicalTrials.gov/show/NCT03392220 Recruiting Cancer Institute and Hospital, Chinese Academy of Medical Sciences 2020-09-30
NCT02430675 Irreversible Electroporation(IRE) For Unresectable Laryngeal Neoplasms https://ClinicalTrials.gov/show/NCT02430675 Recruiting Fuda Cancer Hospital, Guangzhou 2020-12-01
NCT02229656 Olaparib and Radiotherapy in Head and Neck Cancer https://ClinicalTrials.gov/show/NCT02229656 Active, not recruiting The Netherlands Cancer Institute 2020-01-14
NCT02217358 Value of Narrow Band Imaging (NBI) Endoscopy in the Early Diagnosis of Laryngeal Cancer and Precancerous Lesions https://ClinicalTrials.gov/show/NCT02217358 Completed University Hospital Ostrava 2016-03-31
NCT02198131 Pulsed Dye Laser in Treating Patients With Post Radiation Dysphonia https://ClinicalTrials.gov/show/NCT02198131 Completed Wake Forest University Health Sciences 2016-06-30
NCT02177838 Cetuximab and Radiation Therapy in Treating Patients With Stage III-IV Head and Neck Cancer https://ClinicalTrials.gov/show/NCT02177838 Recruiting Rutgers, The State University of New Jersey 2020-06-01
NCT02156518 The Efficacy of Vocal Function Exercises for Laryngeal Cancers https://ClinicalTrials.gov/show/NCT02156518 Completed University of Kentucky 2018-01-31
NCT02123511 Acetylcysteine Rinse in Reducing Saliva Thickness and Mucositis in Patients With Head and Neck Cancer Undergoing Radiation Therapy https://ClinicalTrials.gov/show/NCT02123511 Completed Mayo Clinic 2016-03-22
NCT01316757 Carboplatin, Paclitaxel, Cetuximab, and Erlotinib Hydrochloride in Treating Patients With Metastatic or Recurrent Head and Neck Squamous Cell Cancer https://ClinicalTrials.gov/show/NCT01316757 Completed Fox Chase Cancer Center 2015-04-07
NCT02048020 Paclitaxel and Carboplatin Before Radiation Therapy With Paclitaxel in Treating HPV-Positive Patients With Stage III-IV Oropharynx, Hypopharynx, or Larynx Cancer https://ClinicalTrials.gov/show/NCT02048020 Completed Jonsson Comprehensive Cancer Center 2017-01-09
NCT02035527 Sorafenib Tosylate, Cisplatin, and Docetaxel in Treating Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck https://ClinicalTrials.gov/show/NCT02035527 Completed Ohio State University Comprehensive Cancer Center 2017-04-20
NCT03174275 Carboplatin, Nab-Paclitaxel, Durvalumab Before Surgery and Adjuvant Therapy in Head and Neck Squamous Cell Carcinoma https://ClinicalTrials.gov/show/NCT03174275 Recruiting UNC Lineberger Comprehensive Cancer Center 2021-09-01
NCT03258554 Radiation Therapy With Durvalumab or Cetuximab in Treating Patients With Locoregionally Advanced Head and Neck Cancer Who Cannot Take Cisplatin https://ClinicalTrials.gov/show/NCT03258554 Recruiting National Cancer Institute (NCI) 2025-12-31
NCT01984502 CyberKnife Accelerated Hemilarynx Stereotactic Radiotherapy Study for Early-stage Glottic Larynx Cancer https://ClinicalTrials.gov/show/NCT01984502 Recruiting University of Texas Southwestern Medical Center 2023-12-31
NCT01884259 Induction Chemotherapy With TP+5-FU or TP+Cetuximab Followed by Radioimmuptherapy for Locally Advanced or Not Resectable SCCHNN https://ClinicalTrials.gov/show/NCT01884259 Active, not recruiting Arbeitsgemeinschaft medikamentoese Tumortherapie 2021-01-31
NCT01847326 Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Carboplatin Followed By Chemoradiation in Treating Patients With Recurrent Head and Neck Cancer https://ClinicalTrials.gov/show/NCT01847326 Recruiting University of Chicago 2021-04-30
NCT01810913 Radiation Therapy With Cisplatin, Docetaxel, or Cetuximab After Surgery in Treating Patients With Stage III-IV Squamous Cell Head and Neck Cancer https://ClinicalTrials.gov/show/NCT01810913 Active, not recruiting National Cancer Institute (NCI) 2027-01-01
NCT01806675 18F-FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis Therapy https://ClinicalTrials.gov/show/NCT01806675 Completed Stanford University 2016-12-07
NCT01637194 Cetuximab and Everolimus in Treating Patients With Metastatic or Recurrent Colon Cancer or Head and Neck Cancer https://ClinicalTrials.gov/show/NCT01637194 Completed Fox Chase Cancer Center 2011-07-31
NCT01633541 Chemotherapy AND Bcl-xL Inhibitor (AT-101) For Organ Preservation In Adults With Advanced Laryngeal Cancer https://ClinicalTrials.gov/show/NCT01633541 Active, not recruiting University of Michigan Rogel Cancer Center 2021-11-30
NCT01626638 Confocal Micro-endoscopy in Head and Neck Cancer/Micro Endoscopie Confocale (MEC)Oto-Rhino-Laryngologie (ORL) https://ClinicalTrials.gov/show/NCT01626638 Completed Gustave Roussy, Cancer Campus, Grand Paris 2017-05-24
NCT01473784 Transoral Robotic Surgery in Treating Patients With Benign or Malignant Tumors of the Head and Neck https://ClinicalTrials.gov/show/NCT01473784 Recruiting Ohio State University Comprehensive Cancer Center 2020-12-31
NCT01469429 Phase 1b Food Based Modulation of Biomarkers in Human Tissues at High-Risk for Oral Cancer. https://ClinicalTrials.gov/show/NCT01469429 Completed Ohio State University Comprehensive Cancer Center 2014-09-17
NCT01445405 Radiation Therapy and Bortezomib and Cetuximab With or Without Cisplatin to Treat Head and Neck Cancer https://ClinicalTrials.gov/show/NCT01445405 Completed National Institutes of Health Clinical Center (CC) 2010-08-27
NCT01435252 A Phase II Study In Patients With Advanced Head And Neck Cancer Of Standard Chemoradiation And Add-On Cetuximab https://ClinicalTrials.gov/show/NCT01435252 Completed University of Zurich 2017-10-25
NCT01365169 Post-op Wellness Program for Pancreatic Cancer Patients That Uses Patient Feedback and Real-time Provider Monitoring https://ClinicalTrials.gov/show/NCT01365169 Recruiting M.D. Anderson Cancer Center 2025-02-25
NCT01334177 TLR8 Agonist VTX-2337 and Cetuximab in Treating Patients With Locally Advanced, Recurrent, or Metastatic Squamous Cell Cancer of Head and Neck https://ClinicalTrials.gov/show/NCT01334177 Completed University of Washington 2014-06-30
NCT01332682 Resistance Training and Physical Functioning in Head and Neck Cancer Patients https://ClinicalTrials.gov/show/NCT01332682 Completed University of Alabama at Birmingham 2010-12-31
NCT04278638 IORT in Local Advanced Laryngocarcinoma https://ClinicalTrials.gov/show/NCT04278638 Recruiting Tianjin First Central Hospital 2022-07-01
NCT04174950 Perioperative ERAS Based Nursing Intervention for Laryngeal Cancer Patients https://ClinicalTrials.gov/show/NCT04174950 Recruiting Second Affiliated Hospital, School of Medicine, Zhejiang University 2020-06-30
NCT04110249 Photoacoustic Imaging for Measuring Tumors and Normal Tissue in Patients With Head and Neck Cancer https://ClinicalTrials.gov/show/NCT04110249 Recruiting Roswell Park Cancer Institute 2020-07-13
NCT04057209 VoiceS: Voice Quality After Transoral CO2-Laser Surgery Versus Single Vocal Cord Irradiation for Larynx Cancer https://ClinicalTrials.gov/show/NCT04057209 Recruiting University Hospital Inselspital, Berne 2023-11-30
NCT04030455 Cisplatin, Docetaxel, and Pembrolizumab in Treating Patients With Stage II-III Laryngeal Cancer https://ClinicalTrials.gov/show/NCT04030455 Recruiting M.D. Anderson Cancer Center 2021-10-31
NCT03759431 Vocal-cord vs. Complete Laryngeal Radiotherapy for Early Glottic Cancer https://ClinicalTrials.gov/show/NCT03759431 Recruiting Centre hospitalier de l’Université de Montréal (CHUM) 2024-12-12
NCT03653039 Comparison Between a Standard Tube and the Ultra-thin Tritube for Intubation of the Trachea and for Maintaining Access to the Trachea After Anaesthesia, in Patients With an Expected Difficult Direct Laryngoscopy https://ClinicalTrials.gov/show/NCT03653039 Recruiting Rigshospitalet, Denmark 2019-03-31
NCT03602079 Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Gene https://ClinicalTrials.gov/show/NCT03602079 Recruiting Klus Pharma Inc. 2020-10-31
NCT03548285 Stereotactic Ablative Radiotherapy for Early-stage Glottic Larynx Cancer https://ClinicalTrials.gov/show/NCT03548285 Recruiting University of Texas Southwestern Medical Center 2021-12-31
NCT01155609 L-lysine in Treating Oral Mucositis in Patients Undergoing Radiation Therapy With or Without Chemotherapy For Head and Neck Cancer https://ClinicalTrials.gov/show/NCT01155609 Completed University of Washington 2011-12-31
NCT01045057 Clinical Feasibility of New Tracheoesophageal Puncture Set https://ClinicalTrials.gov/show/NCT01045057 Completed Atos Medical AB 2011-03-31
NCT01044433 Capecitabine and Lapatinib Ditosylate in Treating Patients With Squamous Cell Cancer of the Head and Neck https://ClinicalTrials.gov/show/NCT01044433 Completed Abramson Cancer Center of the University of Pennsylvania 2015-09-24
NCT00970502 Erlotinib, Celecoxib and Reirradiation for Recurrent Head and Neck Cancer https://ClinicalTrials.gov/show/NCT00970502 Completed Icahn School of Medicine at Mount Sinai 2010-11-30
NCT00939627 Phase II Randomized Trial of the Combination of Cetuximab and Sorafenib or Single Agent Cetuximab https://ClinicalTrials.gov/show/NCT00939627 Completed National Cancer Institute (NCI) 2013-01-31
NCT00827164 Resistance Training During Radiation Therapy for Pharyngeal or Laryngeal Cancer https://ClinicalTrials.gov/show/NCT00827164 Completed University of Alabama at Birmingham 2015-04-30
NCT03028766 WEE1 Inhibitor With Cisplatin and Radiotherapy: A Trial in Head and Neck Cancer https://ClinicalTrials.gov/show/NCT03028766 Active, not recruiting University of Birmingham 2019-10-31
NCT04162873 Celecoxib Through Surgery and Radiation Therapy for the Treatment of Advanced Head and Neck Cancer https://ClinicalTrials.gov/show/NCT04162873 Recruiting University of Utah 2024-10-12
NCT00765011 TPF Plus Radiotherapy and Cetuximab to Avoid Total Laryngectomy in Patients With Larynx Cancer https://ClinicalTrials.gov/show/NCT00765011 Completed Grupo Español de Tratamiento de Tumores de Cabeza y Cuello 2014-02-28
NCT00721799 F-18 Fluorothymidine PET Imaging for Early Evaluation of Response to Therapy in Head & Neck Cancer Patients https://ClinicalTrials.gov/show/NCT00721799 Completed University of Iowa 2014-12-31
NCT00593840 Phase II Trial Evaluating Elimination of Radiation Therapy https://ClinicalTrials.gov/show/NCT00593840 Active, not recruiting Washington University School of Medicine 2014-02-28
NCT00576134 The Objective is to Respond to Patients’ Needs in the Field of Larynx Replacement https://ClinicalTrials.gov/show/NCT00576134 Completed University Hospital, Strasbourg, France 2013-08-31
NCT00534729 Organ Preservation: Weekly Carboplatin & Taxol w/Concurrent RT for Locally Advanced Laryngeal & Hypopharyngeal CA https://ClinicalTrials.gov/show/NCT00534729 Completed King Faisal Specialist Hospital & Research Center 2015-09-30
NCT00513435 Saracatinib in Treating Patients With Recurrent or Metastatic Head and Neck Cancer https://ClinicalTrials.gov/show/NCT00513435 Completed National Cancer Institute (NCI) 2011-03-31
NCT00507767 Dasatinib in Treating Patients With Recurrent or Metastatic Head and Neck Cancer https://ClinicalTrials.gov/show/NCT00507767 Completed National Cancer Institute (NCI) 2010-02-28
NCT00492089 Bevacizumab in Reducing CNS Side Effects in Patients Who Have Undergone Radiation Therapy to the Brain for Primary Brain Tumor, Meningioma, or Head and Neck Cancer https://ClinicalTrials.gov/show/NCT00492089 Completed National Cancer Institute (NCI) 2010-08-31
NCT00470496 Photodynamic Therapy Using HPPH in Treating Patients Undergoing Surgery for Primary or Recurrent Head and Neck Cancer https://ClinicalTrials.gov/show/NCT00470496 Completed Roswell Park Cancer Institute 2011-10-28
NCT00467948 Comparison of 2 Cefazolin Prophylactic Protocol in Laryngectomy Patients https://ClinicalTrials.gov/show/NCT00467948 Completed Tehran University of Medical Sciences NA
NCT00462735 Fluorouracil, Hydroxyurea, Cetuximab and Twice-daily Intensity Radiation Therapy for Advanced Head and Neck Cancer https://ClinicalTrials.gov/show/NCT00462735 Completed Icahn School of Medicine at Mount Sinai 2010-10-31
NCT00410826 Cisplatin and Radiation Therapy With or Without Erlotinib Hydrochloride in Treating Patients With Stage III or Stage IV Head and Neck Cancer https://ClinicalTrials.gov/show/NCT00410826 Completed University of Washington 2012-05-31
NCT00397384 Erlotinib Hydrochloride and Cetuximab in Treating Patients With Advanced Gastrointestinal Cancer, Head and Neck Cancer, Non-Small Cell Lung Cancer, or Colorectal Cancer https://ClinicalTrials.gov/show/NCT00397384 Completed National Cancer Institute (NCI) 2013-06-30
NCT00387335 Sunitinib in Treating Patients With Recurrent and/or Metastatic Head and Neck Cancer https://ClinicalTrials.gov/show/NCT00387335 Completed National Cancer Institute (NCI) 2010-03-31
NCT00169247 Radiotherapy With Cisplatin Versus Radiotherapy With Cetuximab After Induction Chemotherapy for Larynx Preservation https://ClinicalTrials.gov/show/NCT00169247 Completed Groupe Oncologie Radiotherapie Tete et Cou 2011-04-30
NCT00169182 Induction CT by Cisplatin, 5FU With or Without Docetaxel in Patients With T3 and T4 Larynx and Hypopharynx Carcinoma https://ClinicalTrials.gov/show/NCT00169182 Completed Groupe Oncologie Radiotherapie Tete et Cou 2009-04-30
NCT00162708 Very Intense Radiotherapy-Chemotherapy Regimen in Advanced HNSCC https://ClinicalTrials.gov/show/NCT00162708 Completed Gustave Roussy, Cancer Campus, Grand Paris NA
NCT00158652 Accelerated Radiotherapy and Concomitant Chemo-radiotherapy in HNSCC https://ClinicalTrials.gov/show/NCT00158652 Completed Groupe Oncologie Radiotherapie Tete et Cou 2011-03-31
NCT00127465 Investigating the Impact of Tailored Reports on Anxiety Amongst Cancer Patients and Their Confidants https://ClinicalTrials.gov/show/NCT00127465 Completed University of Plymouth NA
NCT00117572 Docetaxel Based Chemotherapy Plus or Minus Induction Chemotherapy to Decrease Events in Head and Neck Cancer (DeCIDE) https://ClinicalTrials.gov/show/NCT00117572 Completed University of Chicago 2016-12-31
NCT00114283 Lapatinib Ditosylate in Treating Patients With Metastatic or Recurrent Head and Neck Cancer https://ClinicalTrials.gov/show/NCT00114283 Completed National Cancer Institute (NCI) 2006-10-31
NCT00103259 Bortezomib With or Without Irinotecan in Treating Patients With Locally Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck https://ClinicalTrials.gov/show/NCT00103259 Completed National Cancer Institute (NCI) 2011-11-30
NCT00101348 Erlotinib and Cetuximab With or Without Bevacizumab in Treating Patients With Metastatic or Unresectable Kidney, Colorectal, Head and Neck, Pancreatic, or Non-Small Cell Lung Cancer https://ClinicalTrials.gov/show/NCT00101348 Completed National Cancer Institute (NCI) 2007-10-31
NCT00098631 Lapatinib in Treating Patients With Recurrent and/or Metastatic Head and Neck Cancer https://ClinicalTrials.gov/show/NCT00098631 Completed National Cancer Institute (NCI) 2006-12-31
NCT00096512 S0420, Sorafenib in Treating Patients With Recurrent or Metastatic Head and Neck Cancer https://ClinicalTrials.gov/show/NCT00096512 Completed National Cancer Institute (NCI) 2006-05-31
NCT00095628 SB-715992 in Treating Patients With Recurrent or Metastatic Head and Neck Cancer https://ClinicalTrials.gov/show/NCT00095628 Completed National Cancer Institute (NCI) 2010-07-31
NCT00089362 Alvespimycin Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors https://ClinicalTrials.gov/show/NCT00089362 Completed National Cancer Institute (NCI) 2008-01-31
NCT00004074 Interleukin-12 and Trastuzumab in Treating Patients With Cancer That Has High Levels of HER2/Neu https://ClinicalTrials.gov/show/NCT00004074 Completed National Cancer Institute (NCI) 2009-02-28
NCT00068497 Gefitinib in Treating Patients With Metastatic or Unresectable Head and Neck Cancer or Non-Small Cell Lung Cancer https://ClinicalTrials.gov/show/NCT00068497 Completed National Cancer Institute (NCI) 2007-12-31
NCT00004256 Sargramostim to Prevent Mucositis in Patients Receiving Radiation Therapy for Laryngeal Cancer https://ClinicalTrials.gov/show/NCT00004256 Completed National Cancer Institute (NCI) NA
NCT00063895 Erlotinib in Treating Patients With Advanced Non-Small Cell Lung Cancer, Ovarian Cancer, or Squamous Cell Carcinoma of the Head and Neck https://ClinicalTrials.gov/show/NCT00063895 Completed National Cancer Institute (NCI) 2005-10-31
NCT00055913 Bevacizumab and Erlotinib in Treating Patients With Recurrent or Metastatic Head and Neck Cancer https://ClinicalTrials.gov/show/NCT00055913 Completed National Cancer Institute (NCI) 2007-09-30
NCT00055770 Erlotinib Plus Docetaxel in Treating Patients With Locally Advanced, Metastatic, or Recurrent Head and Neck Cancer https://ClinicalTrials.gov/show/NCT00055770 Completed National Cancer Institute (NCI) 2006-12-31
NCT00049283 Erlotinib, Docetaxel, and Radiation Therapy in Treating Patients With Locally Advanced Head and Neck Cancer https://ClinicalTrials.gov/show/NCT00049283 Completed National Cancer Institute (NCI) 2008-02-29
NCT00033618 Ixabepilone in Treating Patients With Metastatic or Recurrent Squamous Cell Cancer of the Head and Neck https://ClinicalTrials.gov/show/NCT00033618 Completed National Cancer Institute (NCI) 2007-01-31
NCT00031681 7-Hydroxystaurosporine and Irinotecan Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors or Triple Negative Breast Cancer (Currently Accruing Only Triple-negative Breast Cancer Patients Since 6/8/2007) https://ClinicalTrials.gov/show/NCT00031681 Completed National Cancer Institute (NCI) 2011-01-31
NCT00030498 Erlotinib in Treating Patients With Solid Tumors and Liver or Kidney Dysfunction https://ClinicalTrials.gov/show/NCT00030498 Completed National Cancer Institute (NCI) 2007-07-31
NCT00023959 Bevacizumab, Fluorouracil, and Hydroxyurea Plus Radiation Therapy in Treating Patients With Advanced Head and Neck Cancer https://ClinicalTrials.gov/show/NCT00023959 Completed National Cancer Institute (NCI) 2010-03-31
NCT00026975 Efficacy of Hyperbaric Oxygen Therapy in Laryngectomy Patients https://ClinicalTrials.gov/show/NCT00026975 Completed National Center for Complementary and Integrative Health (NCCIH) NA
NCT00359645 Randomized Trial to Assess the Impact of a Screening Program on Upper Aerodigestive Tract Cancer Mortality in a High Risk Population https://ClinicalTrials.gov/show/NCT00359645 Completed Gustave Roussy, Cancer Campus, Grand Paris 2015-12-18

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT03134976 Wound Complications in Head and Neck Surgery https://ClinicalTrials.gov/show/NCT03134976 Completed University of Michigan 2020-04-01
NCT03010150 Blood Tests and Questionnaires in Studying Adherence to Preventative Swallowing Exercises in Participants With Metastatic Head and Neck Cancer https://ClinicalTrials.gov/show/NCT03010150 Recruiting M.D. Anderson Cancer Center 2019-12-31
NCT02245100 Circulating Tumor DNA in Predicting Outcomes in Patients With Stage IV Head and Neck Cancer or Stage III-IV Non-small Cell Lung Cancer https://ClinicalTrials.gov/show/NCT02245100 Recruiting Thomas Jefferson University 2020-07-31
NCT01700647 Breath Testing in Early and Late Larynx Cancer https://ClinicalTrials.gov/show/NCT01700647 Completed Royal Brisbane and Women’s Hospital 2014-10-31
NCT03896958 The PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology) https://ClinicalTrials.gov/show/NCT03896958 Recruiting SpeciCare 2021-03-12
NCT03747783 Nomograms to Precisely Predict Conditional Risk of Survival for Patients With Laryngeal Cancer https://ClinicalTrials.gov/show/NCT03747783 Recruiting First Affiliated Hospital, Sun Yat-Sen University 2019-01-03
NCT03604601 Analysis of the Curative Effect of Salvage Surgery on Recurrent Laryngeal Carcinoma https://ClinicalTrials.gov/show/NCT03604601 Completed First Affiliated Hospital, Sun Yat-Sen University 2018-06-01
NCT03595410 Nomograms to Precisely Predict Conditional Risk of Recurrence for Patients With Laryngeal Cancer https://ClinicalTrials.gov/show/NCT03595410 Recruiting First Affiliated Hospital, Sun Yat-Sen University 2020-01-01
NCT03585075 Characterization of the Autofluorescence of Healthy and Pathological Tissues of Vocal Cords https://ClinicalTrials.gov/show/NCT03585075 Completed Centre Hospitalier Universitaire de Besancon 2014-02-28
NCT01257633 Surgical Treatment of Early Stage Glotto-supraglottic Laryngeal Cancer Via Transoral Resection With Robotic Assistance https://ClinicalTrials.gov/show/NCT01257633 Completed Centre Hospitalier Universitaire de NÄ«mes 2013-12-31
NCT01104714 Pharmacogenetic Response to Chemotherapy Induction for ORL Cancers https://ClinicalTrials.gov/show/NCT01104714 Completed Centre Hospitalier Universitaire de NÄ«mes 2014-07-31
NCT01089803 Observational Study of Swallowing Function After Treatment of Advanced Laryngeal Cancer https://ClinicalTrials.gov/show/NCT01089803 Completed University of Minnesota 2015-08-31
NCT01084733 Nicotine Levels With Response Rates to Radiation Alone or With Chemo In Head & Neck Cancer https://ClinicalTrials.gov/show/NCT01084733 Active, not recruiting University of Kentucky 2021-02-28
NCT00600223 Functional Voice and Speech Outcomes Following Surgical Voice Restorations: A Comparison of Pharyngeal Construction Approaches https://ClinicalTrials.gov/show/NCT00600223 Completed Memorial Sloan Kettering Cancer Center 2010-10-31
NCT00160095 Patient Selection for Hypoxia Modifying Treatments in Larynx Carcinomas https://ClinicalTrials.gov/show/NCT00160095 Completed Radboud University 2010-03-31
NCT00011492 Patient Evaluation for Head and Neck Surgery Branch Studies https://ClinicalTrials.gov/show/NCT00011492 Recruiting National Institutes of Health Clinical Center (CC) NA
NCT00001603 The Effects of Upper Airway and Digestive Tract Tumors on the Immune System https://ClinicalTrials.gov/show/NCT00001603 Completed National Institutes of Health Clinical Center (CC) NA

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT02012699 Integrated Cancer Repository for Cancer Research https://ClinicalTrials.gov/show/NCT02012699 Recruiting University of Nebraska 2099-12-31
NCT03452774 SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry https://ClinicalTrials.gov/show/NCT03452774 Recruiting Massive Bio, Inc. 2021-12-31